How can we do a Reverse Technology Process?

Kishna Vijayaraghavan @Kishna_Vijayaraghavan

04 April 2014 0 5K Report

Target identification -> HTVS -> Glide XP -> e-pharmacophore mapping?

Badges
Science topic

More Kishna Vijayaraghavan's questions See All

How can I interpret HEX server protein-protein docking results?

I've got two files, *.hex and *.pdb files. I want to see the interactions between those two proteins. How can I see it?

03 April 2014 10,167 2 View

How can I predict the IC50 value for a ligand with the help of an occupancy value?

I have the occupancy value (Binding area value of my protein docked with my ligands). Can I predict the IC 50 value?

03 April 2014 2,989 3 View

Does anyone know how PPAR-Gamma is related to Type II Diabetes?

see above

03 April 2014 456 3 View

Can anyone tell me what K-mean clustering means?

In what bases does K-mean clustering separate data?

02 March 2014 7,575 6 View

How can I generate a heatmap using the docked file data I have collected? .

Which server can use for heatmap generation? I have the docked file data (3 PDB files).

02 March 2014 10,021 0 View

Is there any software or online server to do cluster analysis ?

Cluster Software programs: I have a set of compounds ( say 10000 ); I want to cluster them or group them into certain properties( say structures). How can I group them? Is there any software or...

01 February 2014 2,166 3 View

Can I use e-Pharmacophore on any web server?

see above

01 February 2014 4,465 1 View

Can anybody provide a small paragraph about e-pharmacophore?

e-pharmacophore explanation.

01 February 2014 8,021 1 View

Does anyone know how to view the alignment results in ESPript?

I have given the clustalw (*.aln file) as input and given the submit button,but it doesn't shows any alignment result or images? How to view the output files?

01 February 2014 9,870 3 View

Why did the authors extrapolate a phenotype that they experimentally proved in one bacterial strain across the whole genus of the organism?

I aim to be as skeptical as possible regarding whether a pair of orthologous genes results in the same phenotype in their different but related bacterial organisms under similar environmental...

05 August 2024 6,787 4 View

Can anyone provide me with molecular docking softwares/ websites?

Molecular docking software/ websites?

02 August 2024 8,704 7 View

Seeking Software Recommendations for SELEX NGS Data Analysis?

I am looking for software to help analyze SELEX NGS data, including alignment, sequence enrichment, and other related tasks. Can anyone recommend suitable tools or software? Best wishes, Waleed

30 July 2024 1,061 5 View

Could you try using PeptiCloud and see if it's a useful tool for biology research?

PeptiCloud (www.pepticloud.com) is a bioinformatic platform that allows researchers to organize and share their data for their projects as well as collaborate with others in one place. Through...

28 July 2024 4,762 2 View

AutoGrid and Autodock 4.2.6 window opens for 1 second then closes and there is no output files?

Good day, I am a student trying to work on Autodock for a project regarding Ligand-DNA interaction so i am quite new to molecular docking. i have followed tutorials and did all the steps...

28 July 2024 2,136 4 View

Is it possible to dock more than one drug in the same active site or pocket of a protein to study synergistic/antagonistic/additive properties?

I wanted to know whether we can observe the synergistic/antagonistic/additive properties of combinations or mixtures of compounds through docking analysis. But during docking preparation any...

28 July 2024 7,413 6 View

Should the amount of DNA input used for ChIP-seq library preparation be matched between the control and experimental groups?

Hi all. As a beginner in ChIP-seq experiments, I hope you understand that the following questions might be somewhat basic. I am planning to perform ChIP-seq or MeDIP-seq analysis to investigate...

28 July 2024 6,938 1 View

Can we find a statistical matrix mechanics equivalent to the Schrödinger equation?

We assume that we can find a statistical matrix mechanics equivalent to Schrödinger's PDE in two consecutive steps: i-Transform the Schrödinger PDE describing the wave function Ψ into its square...

27 July 2024 3,959 4 View

Is it true that there is a physico-statistical meaning to the constant π other than circular geometry but the iron guardians of the SE deny it?

We assume that there is a physico-statistical meaning to the constant π other than circular geometry, but the iron guardians of the Schrödinger equation deny this. The iron guardians of the...

22 July 2024 4,285 9 View

What is the main factor involve in higher binding score performing molecular docking?

A molecule shows the -11.6 kcal/mol and second one -8.0 kcal/mol so why molecule (A) revealed higher binding score. Please explain major factor involve in it.

21 July 2024 954 5 View