How can I predict the IC50 value for a ligand with the help of an occupancy value?

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Akhil Kumar

I have question??

how to find binding area volume for docked complex??

Kishna Vijayaraghavan

Dear Akhil,

I found the binding area volume of docked complex in Maestro Schrodinger using Surface options which will take 4A residues from ur ligand.

So any suggestions about predicting IC50 value Neeraj??