I have developed a syrup at pH 3 of a BCS class II molecule using propylene glycol, beta Cyclodextrin, citric acid, antimicrobial preservative, and sweeting agent. But i every time get precipitation after holding 2 to 3 days. When shake the bottle i found smoke like floating of these precipitation. How can I fix the problem. I am looking forward to your help.
Hiralal Merwade
If you have charecterised the water insoluble compound qualitatively convert it into water soluble salt form by a suitable method and formation of undesired compounds cam be avoided
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Amit Kumar Acharzo
Thank you sir @phil Geis for your valuable comment. I conducted microbial test and found no growth which made me confirm that it is not from microbial contamination.
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