I want to try to induce colon cancer in mice, and then evaluate potency of anticancer drug in these mice. It means I will have to evaluate size of tumor following injection of antitumor drug in several days .
Is there anyone who induce this tumor in mice? Does it have especial protocol?
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Mohmmed Faris
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Injecting the dimethylhydrazine and after two months will develop the cancer
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Zaim Gashi
With one protocol, colon cancer is induced in mice through a series of injections with 1,2-dimethylhydrazine. Mice will develop primarily colon tumors starting at about 3 mo after the first injection. Tumors in the lung, uterus, and small intestine may also be seen, as well as lymphomas.
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Mohmmed Faris
Injecting the dimethylhydrazine and after two months will develop the cancer
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