How can I calculate the cummulative release for adrug in water , I measure the amount of the drug at certain time interval?

27 November 2020 1 5K Report

how can I calculate the cummulative release for a drug in water , I measure the amount of the drug at certain time interval?

Tomasz Grabowski

Hi,

See attached xlsx file, maybe this way?

Hope it helps,

Best regards,

Tomasz

Badges
Science topic

More Ahlam Klalifa's questions See All

Questionnaire what use ?

Nurses' Knowledge and Skills Regarding Care Bundle guideline in Mosul Hospitals

23 January 2024 1,955 0 View

What are the most promising new statistical methods for estimating the effects of treatments in observational studies??

This question is relevant to a wide range of fields, including medicine, epidemiology, and social science. Observational studies are often the only way to study certain research questions, but...

15 October 2023 9,323 2 View

How long does the status "Evaluating Recommendation" usually takes before getting the decision letter?

In the ScholareOne system, after the peer-review is completed, the status changes to "Evaluating Recommendation". How long does this status typically takes before hearing back from the journal editor?

17 July 2022 8,141 16 View

Any suggestions on drug assay or how to count cell death in drug assay?

I am using RO-3306 CDK1 inhibitor drug to get IC50 and my cell lines is stops responding to to the drug and reach IC50 as previously, any suggestions? or other way to count cell death (I am using...

07 February 2022 2,301 2 View

What is the relationship between the natural frequency and the duration of recording of seismic noise?

I've had measurements of seismic noise. I've got Fourier amplitude spectra to get the natural period of soil. what is the relationship between the natural frequency and the duration of recording...

15 November 2021 9,769 7 View

How can I approve that the use of chitosan nanopaticles as a carrier improve the properites on the effieciency aganist larave?

Hi I'm working on encapsulation of insecticide in chitosan NPs as a carrier and used water as a release medium for larval bioassay for 24 hrs but the efficiency is lower than the bulk one and...

15 September 2020 4,234 3 View

What are the most prominent rhetorical devices employed by James Joyce in his piece" A Portrait of the Aritist as a Young Man"?

James Joyce's writing is characterized by the abundant use of rhetorical devices

18 April 2020 7,066 0 View

Is it true when we change the software of statistical analysis the results change?

I already did a statistical analysis for my study by (SPSS) software. Now, I try to use (Smart pls 3) for statistical analysis for the same research. But, I am surprised the results of the testing...

09 April 2020 4,153 3 View

Is there any correlation between SNP in TLR and progression of periodontitis in patients suffering from Herpes virus?

I need to Know if there is any local research correlated with this topic?

30 March 2020 5,180 14 View

What are the guidelines when publishing research in multiple languages ?

When wanting to publish the same research in another language after publishing the English version, what is the process? Do I need to get the publisher's permission? The work will be rewritten...

04 January 2019 8,097 3 View

Is changing the medium during the experiment overestimate the results?

I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...

07 August 2024 2,283 2 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

How can I determine if a drug binds to a ribosome using a Cryo-EM map?

Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...

19 July 2024 2,155 0 View

How to calculate percentage cumulative drug release?

How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...

15 July 2024 4,192 1 View

MTT assay - 6 well plate?

Hi, In the 6 well plate, when I am seeding the cells. Do I add 1ml of complete media to one of the wells for the control at this stage or do I wait unit I am treating the plates to do that? Also...

13 July 2024 9,783 1 View

How to convince decision makers to adjust the legislation to allow opening of drug consumption rooms?

In my country, there is a lot of public outcry in relation to the presence of drug injection and related behaviors in public. Hence at least the bigger cities would probably benefit from the...

08 July 2024 8,903 1 View

Is the use of microcrystalline cellulose MCC 102 in direct compression technology justified, given the low flowability of this excipient?

Hello everyone reading this topic! It is well known that microcrystalline cellulose 102 is recommended for use in direct compression technology, however, like other grades, it has poor flowability...

08 July 2024 2,807 0 View

What are the trending topic to writ e a review article on it?

The topic should relate to pharmacy ,drug, methos of drug discovery, or any other topic but related to dug or pharmaceutical field

02 July 2024 4,031 3 View