How can I analyze flouride through HPLC ? is IC better over HPLC for fluoride analysis or ISE is evergreen? I am Curious to know any better analysis for ionic fluoride which is less time consuming. Implementation of IC over ISE is worth or not?
Perhaps a fluoride selective electrode would be an option for you?
https://www.thermofisher.com/order/catalog/product/9409BN#/9409BN
https://www.mt.com/au/en/home/library/guides/lab-analytical-instruments/fluoride-ion-selective-electrode-application-guide.html
https://www.thomassci.com/scientific-supplies/Fluoride-Ion-Selective-Electrode
The question is missing a description of the sample and the purpose of analysis. It makes quite a difference if you want to measure Fluoride ions in a highly polluted sample with many other anions at the same or even higher concentrations, compared to a simple dilution of e.g. NaF in pure water.
A fluoride selective elcetrode might be an option indeed.
You could also consider using CE.
You included little in the way of details. ISE is labor intensive and has problems with interferences. IC is easy enough to do but the sample should be clean. It is also very expensive to set up. HPLC is a non starter.
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