Exposure to loud sound can cause noise-induced hearing loss, affecting the hearing threshold. We usually talk about temporary threshold shift (TTS) in laboratory animals if the hearing threshold returns to pre-exposure levels in less than 15 days, and about permanent threshold shifts (PTS) if it does not. This is kind of straightforward in case of a one-time sound exposure. But what about in case of repeated moderate noise exposure? Should we measure the hearing threshold 15 days after the LAST noise-exposure? And considering it PTS if it was not recovered and TTS if it was?
I don't believe there is an international consensus on your question. In any case it is a good practice to estimate TTS and PTS effects at 15, 30 and 60 days post exposure , if the experimental setup permits you to do so.
Also consider that the PTS and TTS effects are species dependent with some species ( rats) recovering much faster than others (mice, guinea pigs etc)..
i concur with Stavros above, the effects are animal species dependent, also i have never come across a consensus on the the question at hand.
PTS and TTS vary from species to species. I dont think there is literature for that.
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