What would you recommend as the best textbook on numerical (algorithmic) solutions to partial differential equations?

.... that would be suitable for a senior-level bachelor of Mathematics major? Thank you.

08 September 2018 4,167 0 View

What would you recommend as the best textbook on Partial Differential Equations (PDEs)?

.... that would be suitable for a senior-level bachelor of Mathematics major? Thank you.

08 September 2018 5,315 12 View

What is the evolutionary advantage of having one's brain left hemisphere control the right side of the body & right hemisph. control the left side?

What is the reason for the two brain hemisoheres to control the sides of the body opposite to them? Is this phenomenon also true for lower mammals such as mice, rats and squirrels, for example?

05 June 2018 3,408 13 View

Has anybody applied Fourier transformation on stock market graphs?

If it can be resolved into simple sinusoids, it might be possible to predict stock market behavior, even if only with partial success. But I am sure that there is a straight line component with a...

04 May 2018 4,302 4 View

Can somebody knowledgeable in the field please give me some advice on which text mining software is best for medical and bioinformatics research?

I would like to know. the best one(s) to use, whether free or proprietary. Thanks much!

04 May 2018 6,021 6 View

Can someone recommend a good and clearly-written textbook on "Digital Signal Processing"?

I have no formal training in electrical engineering (where DSP is staple) but I do have a bachelor's degree in mathematics. I prefer a textbook with plenty of examples. Thanks very much in advance!

03 April 2018 4,536 16 View

Are there any good and well-written books or treatises on 'Signal Detection Theory' and 'Theory of Maximizing Signal-to-Noise Ratio' ?

I believe (as do many others) that these two topics are crucial to unraveling key information from data mining results, especially biological DM. However, my observation is that these 2 key...

03 April 2018 497 4 View

Is there any electromagnetic radiation with higher energy than gamma rays and lower energy than ELF?

I was wondering if the upper and lower limits of the electromagnetic spectrum have been extended through modern research. Gamma rays, with energies of 1.24 MeV, constitute the upper limit, and ELF...

03 April 2018 2,533 3 View

I would like to know how the scientific community feels about "independent scholarship." If you have opinion(s) about it, will you please share them?

Independent scholarship is generally and broadly defined as "basic or applied research without affiliation(s) to any college, university or public and private research institutes" (e.g., please...

09 October 2017 3,499 4 View

What are the top three computer simulation software that are useful for making predictions in biology and medicine?

Are they based mostly on Monte Carlo methods? Are there any based on Las Vegas and Atlantic City algorithms?

07 August 2017 5,980 3 View

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02 March 2021 3,060 3 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Do you need the CMV enhancer before the CMV promotor for a proper function of CMV on the gene that follows?

I'm a student and I have to produce a cell line with a knockin for the NRF2 gene with GFP. I have to put a promotor in front of the GFP because the gene will be too far away from the promotor of...

28 February 2021 7,127 2 View

What could be some reasons why unstimulated monocytes are getting activated?

Im doing PBMC isolation -> CD14+ enrichment using magnetic beads -> stimulation setup. My negative control is just cells in cRPMI but they seem to get activated over and over again.

28 February 2021 7,883 3 View

No title

28 February 2021 9,936 2 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View

Unknown debris sheets observed in cell culture flasks?

Hi, We culture neural progenitor cells in T175 culture flasks coated with PLO-Laminin. We have successfully grown these cells with our protocol for months. Recently, we observed large sheets...

25 February 2021 3,443 4 View