I have 500 mL of chloroform in a Schott flask but it's getting kind of full of some particulate impurities. I want to filter it. What's the best procedure to mantain the integrity of the organic solvent? Thanks a lot.
You could vacuum-filter this using a 0.45um, 47mm Durapore PVDF filters by EMD Millipore (Cat. HVLP04700). An all glass 47 mm Filter assembly option would be XX1004700 (300 mL funnel with stopper connection to flask) into a 1L vacuum filtering flask (Cat. XX1004705). Other filter assemblies and filtering flasks available with ground glass connections too. Visit emdmillipore.com for more information.
Dear David,
The answer of Janet is excellent if you are sure that these particles did not produce micro-impurities or impurities that are soluble in chloroform.
I suggest that you conduct distillation of the chloroform. By this method you will very pure chloroform.
Please note, that chloroform is carcinogenic and it is out of use in all research labs. Be careful.
Rafik
Thabks a lot. I use very small quantities (1mL) inside a extraction cabin. Thanks to you too I'm going to try both procedures.
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