Formulation of entacapone for intraperitoneal injection in mice?

More Mike Mcdonald's questions See All

Who of all of you will help TPEOM to re-originate the Earths atmosphere to it original 5 atmospheric elements/gases?

Global ‘Weather’ has stopped, as ‘aqua thermionic instituted by the ‘Global thermo atmospherics has instituted global thermodynamics of 120º C + and thus all waters are, or have boiled into a...

06 August 2024 8,716 0 View

Who of all the Global Scientific community will help me Prof. Dr. Yoshida make way for TPEOM, MEC ~EMC to return the atmospheric gases to the norma ?

TEP presentation caption (The Environmental Project) Re: Why should Washington’s DC, or any country government point of location think of as nowadays of as to being 'tomorrow as to come! if it...

03 August 2024 2,484 1 View

PH is wrong making up Laemmli running buffer; why?

I found the following recipe at Abcam and converted it to 5x to make a stock solution. Running buffer (Tris-Glycine/SDS) 25 mM Tris base 190 mM glycine 0.1% SDS Check the pH and adjust to...

31 May 2024 1,444 2 View

What is your answer, decision for this?

Who of all of you that see, read this will make action' with me to save this world from its NOW happening global thermodynamics of of a very bad exterminating start of 01/05/2047, and into a...

09 March 2024 1,041 18 View

I am looking for datasets containing DXA body composition and anthropometric data in children?

I am looking for datasets to supplement the NHANES datasets.

09 February 2024 1,471 0 View

Non-radioactive EMSA with biotinylated oligo detection by strep-HRP and/or strep-alkaline phosphatase?

Looking to perform a non-radioactive EMSA to study protein binding to ssDNA. Before doing so, I’m looking to optimize detection. The two detection series are: 1) biotinylated oligo, strep-HRP...

01 February 2024 8,161 0 View

Is the researchgate member "Budee U Zaman" a scammer or a bot?

Dear colleagues and members, the researchgate member Budee U Zaman (researchgate.net) copied one of my preprints one-to-one and passed it off as his own work. He only slightly changed the title....

04 January 2024 4,312 1 View

How can I measure hesperidin content of fruit sample Citrus reticulata other than HPLC?

Good day! I am trying to find a way to measure hesperidin content of the peels of my fruit sample (Citrus reticulata), other than HPLC. I plan to ferment my peels with food-derived mixed cultures...

13 October 2023 1,249 2 View

Can you compile a calibration curve with a standard that contains various compounds?

Can you compile a calibration curve with a standard that contains various compounds? For example a fatty acid methyl ester mix given that you know the concentration of each fatty acid in the mix?...

03 October 2023 2,109 1 View

Buffer that works with Primestar GXL?

Anyone know of a buffer that will work adequately for PCR with Takara's Primestar GXL? I have tons of enzyme but am out of buffer. Takara will sell a pack of extra buffer tubes, but it won't...

12 September 2023 2,451 1 View

What are the steps of formulating a herbal extract into a sheep/goat drench?

I am working on natural remedies for de-worming in small ruminant livestocks. Part of my project involves formulation of drench-type product, which I have not much experience in. My experience is...

30 July 2024 9,806 1 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

Does Fentanyl presence in injecting drug user communities require special harm reduction measures?

With Fentanyl already being detected in some countries in Europe, I believe many of us are not educated enough on special needs of injection drug users that use Fentanyl, due to its high strength...

08 July 2024 7,694 3 View

"Dear Researchers, Could anyone here share insights or tips on how to effectively draft a patent in the Nanotechnology field?

"Dear Researchers, I am currently working on a Nanotechnology project and am exploring the process of drafting a patent to protect our innovations. Could anyone here share insights or tips on how...

02 July 2024 9,627 2 View

Calculating the injection volume for a mouse?

I will be administering 5-fluorouracil at a dosage of 50 mg/kg to mice as an I/P injection. Will someone please check my calculation? (Mw: 130.078 g/mol) Max volume to be administered to mice I/P...

23 June 2024 3,847 1 View

How can formulate Phosphorus 52 and Potassium 34 in liquid ?

formulate Phosphorus 52 and Potassium 34 in liquid

03 June 2024 7,589 2 View

What is the physical or chemical background of the thermal behavior of polyester microfiber fabrics?

I am currently working on my bachelor thesis in the field of back injection molding of textiles made of polyester fibers. We have achieved quite good results with thermal treatments to restore the...

01 June 2024 2,457 3 View

What are good sources for solvent parameters for modern formulation buffers for DLS?

I am dealing with some finicky antibodies that like to self adhere a bit in certain buffers. Working towards formulation for dosing we are trying to find good buffers that will minimize this...

30 May 2024 6,490 3 View

Suggestions for successful unclogging of metallic dispensing nozzles?

Dear all, Hoping for ideas / suggestions for unclogging metallic fluid / paste dispense nozzles. Currently we have a metallic dispense nozzle clogged with silver conductive adhesive. We have...

29 May 2024 9,364 1 View

How to make the PINN for integro-differential equation in Tensorflow?

There is a problem of constructing a PINN based on an integro-differential equation in Tensorflow. Its simplified form is shown on the picture. The function h has no analytical solution. The...

22 May 2024 6,881 4 View

Doha Ellakwa

Try to use any suitable surfactant

Christopher Oswald Migoha

Why are you avoiding cyclodextrin ?

Mike Mcdonald

I am concerned that it will bind to the analyte I am trying to measure and perturb the result. Although I am not sure if this will be a problem I want to exclude the possibility.

Faris T. Abachi

Try to use chitosan