If you would like to use samples of your own artwork in a psychology experiment(also conducted by yourself), is this a potential conflict of interest?

The main intention is to avoid the hassle of copyright violation of others' artwork when using them for the experiment. But if you were to request for permission of use of others' images, would...

08 September 2019 6,938 3 View

Does targeting soluble protofibrils of amyloid beta plaques produce any effect on the insoluble sections of the plaques?

Based on the results of phase 2 trial of experimental anti-amyloid drug BAN2401, I was wondering if the positive effect of this antibody on dissolving the fibrils and reducing the cumulative...

06 July 2018 6,880 0 View

What is the outcome of combining antihistamine medications with antipsychotics and antidepressants?

What are the potential interactions between these three classes of drugs and how is their metabolism in an individual affected?

04 May 2018 3,493 4 View

What accounts for the differences between plasma and brain levels of amyloid plaques in Alzheimer's disease patients?

Is there a possible correlational relationship between the two?

03 April 2018 1,974 3 View

How is the effect of dopamine on the cerebrovascular system of the brain? Is it vasodilatory or vasoconstricting?

It seems that dopamine effect on cardiac vessels is mixed and varies with dose? Does this variation also apply similarly to cerebral vessels? Any application of this neurotransmitter in ischemic...

01 February 2018 6,180 2 View

How is the interaction between the brain and heart's magnetic fields like?

Is it possible to measure the brain and heart's magnetic fields in combination so as to study their influence on each other's strength?

01 February 2018 9,055 4 View

Can environment factor(s) play a part in affecting intracranial hypertension?

For example, can the temperature of external surrounding affect the state of cerebrospinal fluid in the brain which in turn leads to intracranial hypertension?

11 December 2017 2,978 3 View

Is there any way to image cerebral vasoconstriction?

Is it possible using angiography, fMRI or PET scan?

11 December 2017 8,492 4 View

What are the causes of psychogenic nonepileptic seizures?

Is stress a major contributor?

11 December 2017 3,981 4 View

Can blood pressure increase occur independently of high cortisol level?

We know that cortisol induces vasoconstriction which leads to increase in blood pressure. But can this relationship be bidirectional such that elevated blood pressure happens prior to cortisol...

10 November 2017 1,334 8 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

How do I choose contrasts in SPM8?

I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...

24 February 2021 1,534 2 View

Does anyone have any ideas why drug-resistant malaria is increasing in Southeast Asia even when those drugs are no longer used?

When dealing with bacterial toxins, there are three varieties of microbes that develop in your petri dish: toxic, resistant, and susceptible. Initially, there are only toxic and vulnerable...

21 February 2021 6,084 5 View

What is the most prevalent drug related problem in the developed countries?

Detecting the drug related problems is an important step in the pharmaceutical care plan

21 February 2021 5,421 3 View

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19 February 2021 8,647 3 View

Why use both bead beating and enzymes (lysostaphin and lysozyme) for DNA extraction from sputum samples?

Hello, I have read in a few publications that to extract total DNA from sputum samples, both bead beating and enzymes are used to disrupt the cells. Bead beating is supposed to be efficient in...

18 February 2021 3,360 2 View

How to improve dissolution of neosome?

I have made neosome from herbal drug. Neosomes are stable. But I face problems in dissolution. I used minimum ratio of 1:1:0.25 ( Drug:span 60: Cholesterol and GMs. Now how can I active better...

17 February 2021 3,584 1 View

How to determine the drug loading and the drug release capacity of a polymer micelle using UV spectroscopy?

Currently, I am working on PLA-PEG copolymer micelle for the drug delivery system. I have seen several papers where some researcher talks to centrifuge the drug-loaded micelle to separate the...

13 February 2021 5,822 7 View

Should the AUC in a concentration-time graph of a subcutaneous implant be roughly the same for poeple?

I have 2 concentration time curves of a subcut drug implant. the first group has a peak around the 50 day mark where as the second group does not. Both groups received the same implant by the same...

10 February 2021 2,305 3 View