For example, can the temperature of external surrounding affect the state of cerebrospinal fluid in the brain which in turn leads to intracranial hypertension?
Please have a glance through Chapter 5 of my Book, which deals with mechanism of biotransformation and shows that pesticides as environmental carcinogens have the potential to induce intracranial impact on living systems.
Research Book: Pesticides Toxicity Specificity & Politics Chapter 5: ...
Another environmental factor to consider which is likely to affect intracranial hypertension would be infection. This could be through inflammatory factors that cross the blood brain barrier, or through transport to the brain by way of the recently identified lymphatic vessels in the brain.
Hi Kong,, very good question. There are many causes of raised intracranial pressure. Brain tumor, vit A toxication, obesity, drugs, venous sinus thrombosis many other causes can cause raised intracranial hypertension. Temperature have important role in controlling intracranial pressure. Hyperthermia can dysregulate intracranial blood flow and can can raised intracranial pressure. On the other hand hypothermia can reduce intracranial pressure. Following article might help you..