Dear Salma Abdelmaboud ,

To edit Immunohistochemistry (IHC) images, you can use several software options that are suitable for scientific image processing, among the following.

(1.) ImageJ/Fiji (https://imagej.net/software/fiji/downloads): This is a powerful, open-source image processing program that is widely used in scientific research. You can use plugins to enhance images, remove artifacts like bubbles, and change background colors. The “Color Deconvolution” plugin can help you separate stains, and you can adjust the background using the “Enhance Contrast” feature.

(2.) Photoshop(https://www.adobe.com/products/photoshop/free-trial-download.html): Adobe Photoshop is a professional image editing tool that provides advanced features for editing IHC images. You can easily remove unwanted bubbles using the clone stamp or healing brush tools, and you can change the background color using layer adjustments.

(3.) GIMP(https://www.gimp.org/downloads/): Similar to Photoshop but free and open-source, GIMP offers a range of editing tools. You can use the healing tool or clone tool to remove bubbles and adjust colors using the “Colors” menu for background modifications.

(4.) BioImage Suite(https://www.slicevault.com/): This software is tailored for biological image analysis and provides tools specifically for processing and analyzing IHC images.

Note: Make sure to keep a copy of your original image in case you want to revert to it later.

Hope this helps,

Shafik