If genetic drift causes to homogeneous population with strong characters to survive in a particular environment, how does inbreeding lead that to a weak, unstable population...?
Inbreeding has no effect on genetic drift. Inbreeding causes however stronger selection against recessive deleterious traits. Populations where deleterious genes become fixated as a consequence of random effects (genetic drift) may loose their viability (as seems to be the case for animals where only a few individuals are still alive)
I do not know if this is the answer to the question posed, as this question is not very clearly stated...
I agree with your statement. So, from the point of population genetic to select a strength population for aquaculture development, how we clear out isolated population with inbreeding is getting weaker reducing genetic diversity, but they have a stronger selection of traits for that environment....?
I interpret the question as a question about optimal breeding strategies for fish. In general, one should avoid loosing genetic diversity too quickly because genetic gains will tend to become less for multifactorial traits if the genetic diversity decreases. As a Human geneticist I am however not particularly able to answer those questions. The University of Wageningen, the Netherlands, has a world class animal breeding group, headed by Prof Johan van Arendonk. I suggest that you contact this group, perhaps they can lead you to relevant literature and give some suggestions.
Genetic drift works in large and small populations but it has clear effects on small populations only through the founder effect or bottle neck effect , and this occur by chance , so we call it dispersion factor with unknown direction for increase gene frequency or decrease it . But I suggest from your question that you talk about natural selection which decrease deleterious genes , almost been recessive gene , and if the gene has selection feature and benefit for the genotype by increase viability and fertility , in this situation the gene frequency for this allele will be high .
As underlined by the two previous colleagues, there is a lot of randomness in the fixation of traits. Also, overdominance, i.e. superiority of heterozygotes over homozygotes, may also be an explanatory factor the lack of fitness of inbred populations...
dear friend, I think you want to know that if inbreeding increases homogenous group than dominant trait will become homogenous and it definately give better phenotype in next generation than why all says that inbreeding gives deliterious effect?....if my thinking is right than answer is... inbreeding show there effect if effective population size is not there and when they affect and dominant gene get homogenize same way recessive traits may also homogenize and they may be on the side of good penotype or bad phenotype.... other thing is genetic variability that play most effective role by heterosis and that will decease in next generations of inbreeding.... one morething is that as population become homogenous there reproductive problems increases (why that i am also not clear)