There are several studies that claim that belonging to one blood group rather than another may influence the course of the disease. On what basis of clinical and molecular pathology is this hypothesis based? Could this be confusing data or is it based on strong and consolidated evidence?
It is difficult to answer you. It seems that some blood groups (e.g., O) can promote a rapid immune response against some infectious agents such as SARS-CoV-2. However, I personally believe that robust scientific evidence is still lacking to confirm this hypothesis.
Thank you for the answer. It isn't simple to explain the data from the pathogenetic point of view.
There are few studies that suggest blood group A is more susceptible to develop covid-19 related complications and blood group O is less susceptible. However, more supporting data is needed to prove the same.
This article may be useful:
“Have anti glycoprotein antibodies a role?”
doi:10.1016/j.mehy.2020.110036PMCID: PMC7314692PMID: 32652428
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