We are in discussions with Agilent to acquire a custom mutation and fusion panel. They introduced us to the pre-capture polling solution. I would like to know about the experience of those who have worked with Agilent, if it was a good experience.
Agilent Technologies offers a range of NGS solutions for mutation and fusion detection in various research applications, including cancer genomics and molecular pathology. Here are a few Agilent products commonly used for mutation and fusion analysis:
SureSelect XT HS: SureSelect is an NGS target enrichment system designed to capture specific genomic regions of interest. The SureSelect XT HS (High Sensitivity) assay enables the enrichment of both DNA and RNA targets, facilitating the detection of genomic alterations, including point mutations, small insertions and deletions (indels), and gene fusions.
HaloPlex Target Enrichment System: The HaloPlex system is another target enrichment solution by Agilent. It allows for the capture and amplification of genomic targets using a single-tube workflow. HaloPlex can be used to detect mutations, indels, and gene fusions in both DNA and RNA samples.
SureCall software: Agilent's SureCall software is designed to analyze and interpret NGS data, including mutation and fusion events. It provides variant calling, annotation, and visualization tools for accurate and efficient data analysis.
Agilent NGS solutions incorporate various technologies, such as hybridization capture and PCR-based enrichment, to capture sequence-specific genomic regions of interest. These solutions are often combined with powerful bioinformatics tools and analysis pipelines to detect and interpret mutations, fusions, and other genomic alterations.
To get more detailed and specific information about Agilent NGS products for mutation and fusion analysis, it is recommended to visit the Agilent website, explore the product documentation and technical specifications, or reach out to Agilent support or sales representatives who can provide further assistance based on your specific research needs. Additionally, seeking insights from researchers or scientists who have used Agilent NGS products in their mutation and fusion studies can provide valuable practical experiences and tips.