The blood comes from a pregnant woman. And was not lipaemic.
It is likely cryoglogulins. Cooling down of blood as it occurs during centrifugation can cause cold agglutinins to precipitate. The other possiblility would be cryoglobulins, due to chronic hepatitis B or C as well as any chronic inflammatory process. Myeloma paraprotein is another yet remote possibility. If this is due to IgM, ask your blood bank for DTT, di-trio-trietol, which will break down the IgM molecule. Remember that pregnancy has increased sed rate and is a pro-coagulant state.
This is not cryoprecipitate, since I take it you have not frozen this sample. Pregnancy is a pro
Dear: Malgorzata
I think this is a fibrin because a cause is clot time is short in tube blood collection for example some manufacturer recomended 30 minutes minimun un tube whit gel barrier and 60 minute un whitout gel barrier, this depend coagulation patients other cause is short time centrifugation but not is common.
Best regard
It isn't answered clearly, but it's probably regarded as a fibrin. Best regard
It is fibrin. We often see that phenomen when producing autologous serum eye drops from patients under medication for anticoagulation.To prevent this you can wait longer (up to 24 h) before centrifugation and you should not cool down the blood before centrifugation. But in some cases you cant do anything against the clots.
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