I want to run Native PAGE for my G-quadruplex forming Oligonucleotides in presence of a specific metal ion and also to stain it for visualization.Also it is already known that Ethidium Bromide is a weak binder for G-quadruplex. Our lab have Stains-all and Silver stain available. Our lab is new to this topic and no one in our lab has experienced about this.I have tried using some online protocol 2-3 times but it does not work good. Does anyone of you are using this techniques in your lab and if yes, can you please share the protocols for the same.I would be highly obliged.