I'd like to study human resistance to alkaloids of the vinca cell line.
There are HEK293 cells with transfected Pgp/MDR1/ABCB1 or a ton of MCF-7 drug resistant sublines that overexpress Pgp, eg MCF-7 ADR.
All should be resistant to vincristine based on transport efflux
Yes, insect gut cell line are resistant to alkaloids
screening of 94 cancer cell lines shows that OU31 and Caco2 cell lines are most resistant to vincristine, which may be related to overexpression of pgp in these cell lines.
Dear community, I am rather new to phylogenetic comparative methods and seek your advice. I want to compare a continuous trait (dependent) between species belonging to either groupA and groupB...
22 September 2020 1,618 4 View
Hi there, my name is Panagiotis Koilakos and I am studying computer science in AUEB, Greece. During an HCI(Human-Computer Interaction) course, we had to select a home device and try to beautify it...
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Dear community members, We have available WGBS data for a species. We used Bismark to map the reads to the reference genome. Unmethylated lambda phage DNA was spiked-in, to estimate the bisulfite...
18 July 2018 4,081 2 View
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18 November 2017 9,012 3 View
Different forms of sulfur containing compounds.
04 July 2017 9,495 9 View
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25 June 2017 7,371 0 View
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26 March 2016 3,983 4 View
03 March 2021 8,272 1 View
I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...
03 March 2021 4,116 4 View
02 March 2021 3,060 3 View
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Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...
02 March 2021 3,024 2 View
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02 March 2021 8,437 2 View
Hello, I would like to ask how to grow E.coli which resists 50 or 100ug/ml of Blasticidin. I have tried many methods by using low salt Luria-Bertain(LB) agar plate. However, no colonies grow. Let...
01 March 2021 2,027 2 View
Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...
01 March 2021 3,867 3 View
Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?
01 March 2021 8,087 3 View
We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...
01 March 2021 3,355 3 View