I would like to perform an experiment to inhibit Mn-Sod in living fibroblast cells to observe how they would cope with the increased oxidative stress.
Thank you in advance!
A list of substances that have been tested for inhibition of Mn-SOD can be found here:
http://brenda-enzymes.org/enzyme.php?ecno=1.15.1.1#INHIBITORS
Most of the things on the list are obviously not specific.
A shorter list of inhibitors of human Mn-SOD can be found here:
http://brenda-enzymes.org/enzyme.php?ecno=1.15.1.1&Suchword=&reference=&UniProtAcc=&organism%5B%5D=Homo+sapiens&show_tm=0#INHIBITORS
I need to model an anisotropic material in which the Poisson's ratio ν_12 ≠ ν_21 and so on. Therefore, the elastic compliance matrix wouldn't be a symmetric one. In ANSYS APDL, for TB,ANEL...
09 August 2024 5,048 2 View
I isolated microbial DNA from marine water samples taken at various sites using the Qiagen Power Water DNA Isolation Kit, including a modified enzymatic lysis step. I encountered a situation where...
24 July 2024 9,688 0 View
1. Nutritional contribution of the edible coating 2. Self life of the vegetable to be coated with the edible coating. 3. Toxicity development after preserving the vegetable with the edible coating.
11 June 2024 1,740 3 View
I am using 20 mg of WO3, 800 mg of Sulphur, 925 oc growth temp, 280 oc S temp, and a 20 sccm gas flow rate.
05 May 2024 8,665 2 View
I have questions regarding the safe use of cell phones in animal research facilities. While I acknowledge the hygienic risk, we often spend a lot of time inside our barrier SPF facility and we...
14 April 2024 3,486 0 View
Ladies and Gentleman, My name is Jana Maric, and I am a tourism management student at the university of applied sciences in Germany currently researching for my bachelor´s thesis in the field of...
08 April 2024 4,449 0 View
Please do it by hand, if not possible just do by some analytic engine.
26 March 2024 2,028 0 View
I deposited Ga2O3 thin film on fused quartz substrate at 500oc in Ar ambient by RF sputtering and then annealed at 900oc (very slow heating and very slow cooling i.e 1oc/min) in air ambient for 1...
11 February 2024 3,417 4 View
ANSYS multilinear material model does not support plastic strain vs stress data with a negative slope. Moreover, it assumes perfectly plastic (horizontal) behaviour from the end data point. How...
01 February 2024 9,950 0 View
INDIAN JOURNAL OF NATURAL SCIENCES ISSN: 0976-0997 ( Print, Bimonthly ) Multidisciplinary Sciences Web of Science Indexes: Zoological Record is this journal UGC care list II category?
25 December 2023 4,017 2 View
What is the role of oxidative stress in toxin-induced carcinogenesis? I am currently researching the impact of environmental toxins on children's health and would greatly appreciate insights from...
02 August 2024 3,174 1 View
I am currently working on a project that involves extracting cell membranes, for which we disrupt the cells using sonication. During the initial extraction process, we add protease inhibitors to...
30 July 2024 7,077 1 View
I'm new to primary human fibroblast culture and I'm studying aging using cells from old and young donors. Some research groups have used media supplemented with FGF2, so I cultured cells in the...
29 July 2024 3,030 2 View
i compare between the antioxidant and oxidative stress level between negative control rats (saline) and CCL4 intoxicated rats. i found the level of GSH and TAC is more in toxic group than normal....
26 July 2024 1,887 0 View
The aim of the research here is to prevent the propagation of the crack in the fabricated elastic medium with useful applications.
25 July 2024 9,976 3 View
I have to quantify the enzymatic activities of SOD in plants using a method that employs hypoxanthine-xanthine oxidase to create O2. The colorimetric reaction was performed by combining...
23 July 2024 8,492 3 View
"The Correlation between Nutrition and Transport Mechanism under Abiotic Stress in Plants: A Comprehensive Review" by Muhammad Saleem, Jianhua Zhang, Muhammad Qasim, Rashid Iqbal, and Li Song,...
23 July 2024 9,109 0 View
hi every one I am making vector construction (for fusion proteins) and in this moment I wanna to amplification of ADAM17 prodomain with PCR. to yet, I couldn't amplified the ADAM17 prodomain with...
21 July 2024 8,660 1 View
How can alternative crops for augmenting farmers’ income in abiotic stress regions and impact of abiotic environmental stresses on crop quality?
13 July 2024 6,826 5 View
please give me the scoring system of Academic stress scale developed by Rajendra and Kalikapan?
11 July 2024 2,054 3 View