Hi Krishnat,

Did you solve your doubt? I was looking for other TSC question and found yours.

TSC is an autosomal dominant disorder which means that one copy of one of the altered genes (TSC1 or TSC2) is sufficient for disease development. In about 1/3 of cases is inherited (the affected individual inherits it from an affected parent) and 2/3 are sporadic cases (people with no familial history and with a de novo mutation).

Best,

Michele