DLBCL cell lines? - FAQS.TIPS

31 May 2022 1 5K Report

Hey, guys

I would like to know the genotyping of diffuse large B-cell lymphoma cell lines, similar to the TMD8 cell line belonging to the MCD subtype, is there any similar literature?

Amos Bairoch

As it seems that the MCD/BN2/N1/EZB classification of DBCL is not directly mappable to that of the ABC/GCB one, I am not sure of which DBCL cell lines are closest in genetics to TMD8 as currently in the Cellosaurus, the ABC/GCB nomenclature is used.

In any case you can get a full list of DBCL cell lines by doing:

https://web.expasy.org/cgi-bin/cellosaurus/search?input=Orphanet_544

For the next release of the Cellosaurus I will add annotations on the known sequence variations in CD79A, CD79B, CARD11 and MYD88A in TMD8, OCI-Ly3, HBL-1 and other DBCL cell lines. But I could find this type of information only for a relatively small set of DBCL cell lines.

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