How to make sure each cavity modes with same E-field distribution in COMSOL simulation?

In COMSOL Application Library, there is case about waveguide adapter. But there are some questions: 1) In boundary mode analysis, it just set to find only 1 mode and the S-parameter is...

12 January 2021 9,383 2 View

Where to get per-unit ecosystem services value coefficients for cities?

Per-unit ecosystem services value coefficients are wisely used in ecosystem services research, which is usually in the unit of "money per area for certain ecosystem type/services". The ecosystem...

06 January 2021 4,230 3 View

How to detect protein from dying cells?

Hello, experts. I have been struggling during my Western blot. Briefly, I transfected my gene into two different breast cancer cell lines. The introduction of my gene triggered cell death in one...

03 September 2020 8,799 3 View

What's the difference in antibodies used in ELISA,FACS and IHC?

Hello, I have a question about antibodies used in ELISA, FACS, and IHC. Assuming that an antibody is not labeled or conjugated, what's the difference among them? Can I treat those antibodies in...

27 July 2020 716 11 View

How can I generate Deek's funnel plot in R software, not in STATA?

I am conducting Diagnostic test accuracy meta-analysis. For publication bias, I want to conduct Deek's funnel plot test. I am using R software with mada ant meta packages. However, I found that...

16 May 2020 4,368 1 View

How to grow more BL21 auxothrophic strain cells?

Dear all, I have just purchased a BL21 auxothrophic strain (RF12) from Addgene. The cells come in the form of agar stab. I intend to grow more cells which will be ready to used for protein...

11 May 2020 8,384 3 View

Do you know a lipo battery that is smaller than 10mmX9mmX3mm??

Hi everyone, I'm looking for a small/tiny battery that can generate over 3.2V for biocompatible electronics. Currently, I'm using a 3.7V 12mAh Lipo battery and its size is 10mmX9mmX3mm (WLH). I...

08 March 2020 8,641 2 View

Does anybody know how to draw a pie chart with multiple layers?

I found this graph from literature and it's an excellent way to illustrate similar types of ideas in my opinion. I would like to draw this type of graph in my work but I couldn't find the proper...

14 February 2020 5,933 2 View

How to fit the Gaussian curve based on the moment of power spectrum?

I want to make a spectral correction curve of my light source to resemble the Gaussian spectrum. This literature said, ".. The dashed curve is a Gaussian fit with a center wavelength of 833 nm...

20 January 2020 8,950 2 View

Article of hierarchically structered porous nanofibers by electrospinning?

Hello folks I'm looking for the artice which shows difference of hierarchical structures between membranes and nanofibers. From introduction, I remember it kinda said: hierarchical membranes are...

15 September 2019 470 1 View

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02 March 2021 324 2 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

What is the value of Conference Review Paper?

How much value does a review paper carry in a higher study aspirant student's profile which is presented in a Peer Reviewed Scopus Indexed conference?

27 February 2021 2,068 3 View

How do I choose contrasts in SPM8?

I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...

24 February 2021 1,534 2 View

How to empty large intestine in mice ?

Hi all I am working on colon-targeted drug delivery for which I kept mice fasting for 6h using fasting grills during scotophase (dark period). I observed liquid fecal content in the cecum and...

23 February 2021 7,701 2 View

Can I use a protein-devoid condition as my negative control in ELISA?

Hello, I am running a sandwich-type ELISA where I am trying to inhibit a protein-protein interaction using small molecules. For each experiment, I determine my Z' (Z-prime) to determine the...

23 February 2021 7,429 1 View

How does the injection volume impact LLOQ and ULOQ in regression analysis (LC-MSMS)?

Hello, I have run into an issue that has sparkled a debate at work: is the LLOQ/ULOQ impacted by injection volume under the following circumstances: 1) Same dilution factor of all samples 2)...

23 February 2021 9,159 3 View

Can two EC50 values with different hill slopes be compared?

Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...

23 February 2021 8,155 5 View