Databases similar to The Cancer Genome Atlas for other diseases?

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How to estimate sample size when you think the effect size will be reduced (compared to previous studies)?

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Can Stimulus Packages safeguard businesses during the Covid-19 Pandemic?

Research Proposals

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What is the difference between genotype and haplotype data in the ped format?

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How to download dataset?

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Is it possible that Cancer cells could survive in heparinized blood for 48 hours?

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Are there any databases for gene co-expression or expression pattern clustering?

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The PC12 cell line characteristics?

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What is the minimum number of exosomes/ml to have a good yield of total RNA for Illumina sequencing?

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Frederic Lepretre

Hi Ryan

you can dig in the GEO repository for many diseases for which you'll find datasets (https://www.ncbi.nlm.nih.gov/geo/).

all the best

fred

Maryam Rahimi-Tesiye

These databases are also useful:

https://www.genenames.org/

https://www.omim.org/

https://www.ncbi.nlm.nih.gov/gap/

https://www.disgenet.org/

https://www.mutationtaster.org/

Mahshid Arastonejad

The International Cancer Genome Consortium (ICGC): The ICGC is a global effort to map the genomic changes underlying 50 different types of cancer. It provides open access to data on genomic, transcriptomic, and epigenomic changes in cancer tissues, as well as clinical and pathological information.

The Genomic Data Commons (GDC): The GDC is a platform developed by the National Cancer Institute (NCI) that provides genomic and clinical data for cancer research. It includes data from TCGA, as well as other projects such as the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) initiative.

The Accelerating Medicines Partnership (AMP): The AMP is a collaboration between the National Institutes of Health (NIH) and private sector organizations aimed at accelerating the development of new therapies for diseases such as Alzheimer's disease, diabetes, and rheumatoid arthritis. It provides open access to genomic, proteomic, and imaging data for these diseases. https://dbaasp.org/home

The Parkinson's Progression Markers Initiative (PPMI): The PPMI is a global effort to identify biomarkers of Parkinson's disease progression. It provides comprehensive genomic, imaging, and clinical data for Parkinson's disease patients and healthy controls. https://www.ppmi-info.org/access-data-specimens/download-data

The Alzheimer's Disease Neuroimaging Initiative (ADNI): The ADNI is a large-scale research effort aimed at identifying biomarkers for Alzheimer's disease. It provides open access to genomic, imaging, and clinical data for Alzheimer's disease patients and healthy controls. https://adni.loni.usc.edu

Ye'Anqi Jin

BBI-ALLEN SINGLE CELL ATLASES (brotmanbaty.org)

I appreciate its function of cell type composition.

I also work on non-cancer diseases, &hope it could be useful.

Chakit Arora

There are several databases and repositories available that provide genomic data and tools for the study of non-cancer diseases. Here are a few examples:

The Genetic Association Database (GAD) - GAD is a database that collects data from published studies investigating genetic associations with various diseases, including autoimmune disorders, cardiovascular diseases, and neurological disorders. The database includes information on single nucleotide polymorphisms (SNPs), genes, and diseases.

The National Institute of Neurological Disorders and Stroke (NINDS) Repository - The NINDS Repository provides access to biospecimens and genetic data from patients with neurological disorders. Researchers can use this resource to investigate the genetic basis of neurological diseases and to develop potential treatments.

The Online Mendelian Inheritance in Man (OMIM) - OMIM is a database that catalogs genes and genetic disorders. The database includes information on the genetic basis of various diseases, including cardiovascular diseases, neurological disorders, and rare genetic disorders.

The Comparative Toxicogenomics Database (CTD) - The CTD provides information on how environmental chemicals can affect human health. The database includes information on the genes and proteins that are impacted by toxic substances and their associated diseases.

These are just a few examples of the many databases and repositories available for the study of non-cancer diseases. It is important to choose the appropriate resource based on your research question and to make sure that the data and tools are reliable and validated.