Dear Javed,

You can find detailed knowledge in this manuscript that the link of it given below

http://link.springer.com/article/10.1007/s12665-013-2624-4

Ramadan Mubarak

Cem TOKATLI

Hello dear CEM, thank you. would you please attach me the full paper of this link. It is paid so i cant afford it. and also my institution does not have membership of springer. I would be extremely thankful to you.

Dear Javed,

I could not find your email, please send your email adress.

Hi Javed

To clearly answer your question, I think you should search on google to find out the related studies. I recommend you to read one of my paper and find the paper's references and I think that you will answer your question. Good luck with your studies.

Le et al, 2010. Distribution of Trace Metals and Methylmercury in Soft Tissues of the Freshwater Eel Anguilla marmorata in Vietnam. Arch Environ Contam Toxicol

Thank you Le, hope this will help me.

Dear Javed,

The usual mechanisms reported include metallothioneins and other binding proteins like ferritin, ceruloplasmin, and antioxidant defences like Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-s-transferase (GST). Have a look at Sevcikova et al

http://vri.cz/docs/vetmed/56-11-537.pdf

or try googling the various mechanisms.

Good luck with your project.

Anne

As wrote Anne, one of the most effective mechanisms for the accumulation of heavy metals in certain organs of the fish, is a unique susceptibility to the formation of complexes of these metals by certain specific proteins. Just because in some organs of fish are exceptionally high values ​​of bioconcentration factor (or bioaccumulation factor) for heavy metals.

Thanks to all