Correlation between molecular structure and column selection?

With regard, Please suggest that have you experiences straight HPLC column selection by knowing molecular structure. or what are the concept you follows for selection of HPLC column. (i.e....

08 September 2019 846 4 View

WHAT ARE THE MANUFACTURING DIFFERENCE TO FORMULATE A CONTROLLED RELEASE AND SUSTAINED RELEASE DOSAGE FORM?

when formulating a delayed release dosage form what the differences are undertaken in various delayed release formulation e.g.Binders, compression.

10 November 2014 3,890 0 View

How can you know that a sample is uv active?

Please update me- is there any specification on structure basis, that a compound is UV active? As a large molecule, can we make a decision to look into whether the structure of that molecule is UV...

10 November 2014 2,276 7 View

What is the entropy of a dead man?

i had the query to understanding about thermodynamics law. recently i found that thermodynamics is unable to provide a reason behind the entropy of living organism. so how can we know that what is...

10 November 2014 1,835 1 View

Can anyone explain the different principles of HPLC?

Is there any difference in principle of reverse phase chromatography and Normal Phase Chromatography? Please share any link where i can update myself in detail. Thanks and Regard

08 September 2014 5,360 21 View

Column Flow Pattern

Please help me to understand the flow pattern of mobile phase inside the column. please share any link where i can update myself. Thank & Regard

08 September 2014 1,844 0 View

How can I improve my chiral column resolution?

I'm using Chiralpak IA column for my analysis. initially there was good resolution in my analysis, but followed by time the both peak in racemic merged. My mobile phase is only n-Hexane:IPA...

08 September 2014 4,681 9 View

Problem With CHIRAL PAK AD-H Column - Can anyone help?

I used Chiralpak AD-H column, and my molecule having THF, MDC in traces. So within 1 month the column gives a poor peak and also tailing with peak broadening. I tried ethanol, IPA for washing as...

08 September 2014 7,455 13 View

Looking for Materials with high thermal expansion coefficient and high temperature resistance?

03 March 2021 8,272 1 View

Guidelines for survey (question type) analysis?

Hi. Please tell me what guidelines should i need to follow for questionaries' type research work in India. It is not hospital based work, we are conduction basic institutional based qualitative...

03 March 2021 2,037 3 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

Waters 2707 HPLC autosampler problem?

I am using a 2707 waters HPLC device. When I try to inject a sample, it says missing plate or rack. I changed the needle and calibrated its position but I still get the same problem. I even get...

02 March 2021 1,408 1 View

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02 March 2021 932 1 View

Why almost every element would be metallized in sufficiently high pressure and low temperature?

(This statement is from wikipedia, BTW). What is so special about metallic bond that is limiting high-P low-T state of a matter (as long as individual atoms exist, not white dwarf of neutron star...

02 March 2021 3,309 2 View

Is there a powerful system for the security of the systems distributed on IoT systems?

Is there a powerful system for the security of the systems distributed on IoT systems?

02 March 2021 3,858 10 View

How optimize the Size Exclusion Chromatography?

Hello! I'll do a size exclusion chromatography, but I only have an open column, and I'll perform the peptide extraction from yeast, using buffer lysis (sodium phosphate 50 mM/NaCl 30 mM/DNAse and...

01 March 2021 2,215 2 View

Does anyone know HRM channel in a 2 plex QIAGEN Rotor- Gene Q qPCR can be used as a separate channel?

I am going to have 3 different probes in my qPCR work that I am going to do. But I realized that the machine we have in the lab is a Rotor-Gene Q 2plex HRM Platform, saying it has green, yellow,...

01 March 2021 8,544 1 View

I have designed reflectarray element and feeding it though Horn Antenna on HFSS. After full wave simulation, I am not getting desired results?

I have designed reflectarray element to generate OAM beams at 5.8GHz and feeding it though Horn Antenna on HFSS. After full wave simulation, i am not getting desired results i.e Radiation pattern...

01 March 2021 9,701 5 View