Unmasking of asymptomatic COVID-19 cases following vaccination - PubMed (nih.gov)

It is useful in my country Egypt specially in school children's. For travelling outside the country we must take the Corona virus vaccine. I think it is very important.

Cardiology professor Costas Arvanitis has said categorically that children do not need the vaccine whether at home or abroad.

Dear colleague

Please accept our most cordial greetings. Answering your first question, as a result of our experience in the area, I believe that although the configuration of the virus changes, the vaccines will continue to have a protective effect against the virus, although I believe that their effectiveness will no longer be 100%. Therefore, improving the vaccine is essential as there are changes in the conformation of the virus. For your second question, the only thing I can say is that our body's immune response will be less effective, in the case of infections with viruses with mutations, it will still be better than if we had not taken the vaccine. I suggest reading this article of ours, which may help.

https://doi.org/10.1002/hsr2.1058

A big hug and I hope I helped.

Dear colleagues:

Great thanks and gratitude for these scientific answers that indicate your great experiences

Dear Doctor

I chose the following paragraphs from google web hoping of benefit.

"The COVID-19 vaccines that are currently in development or have been approved are expected to provide at least some protection against new virus variants because these vaccines elicit a broad immune response involving a range of antibodies and cells. Therefore, changes or mutations in the virus should not make vaccines completely ineffective. In the event that any of these vaccines prove to be less effective against one or more variants, it will be possible to change the composition of the vaccines to protect against these variants.

While we are learning more, we need to do everything possible to stop the spread of the virus in order to prevent mutations that may reduce the efficacy of existing vaccines. In addition, manufacturers and the programmes using the vaccines may have to adjust to the evolution of the COVID-19 virus: for example, vaccines may need to incorporate more than one strain when in development, booster shots may be required, and other vaccine changes may be needed. Trials must also be designed and maintained to allow any changes in efficacy to be assessed, and must be of sufficient scale and diversity to enable clear interpretation of results. Studies of the impact of vaccines as they are deployed are also essential in order to understand their impact.

Scaling up vaccine manufacturing and rolling out vaccines as quickly and widely as possible will also be critical ways of protecting people before they are exposed to the virus and the risk of new variants. Priority should be given to vaccinating high-risk groups everywhere to maximize global protection against new variants and minimize the risk of transmission. Moreover, ensuring equitable access to COVID-19 vaccines is more critical than ever to address the evolving pandemic. As more people get vaccinated, we expect virus circulation to decrease, which will then lead to fewer mutations."

There is a huge problem with the third and further vaccinations that there are no studies to confirm their clinical effectiveness or ineffectiveness or side-effects, short- and longterm. With studies I mean randomized double blind controlled trials as we had for the first two vaccinations.

What is the role of memory cells? It is proven they are present after two vaccinations.

Make mutations the covid-19 virus less virulent as was seen with the omicron variant? Attenuation of virulence make side-effects more important.

So many questions where a scientific based answer is impossible for the moment.

'In dubio abstinere' is an old medical wisdom.