Hello everyone,
I am trying to make iPSCs by using Yamanaka factors (OSKM). I am confused that should I use human derived factors or mouse derived? At this moment, my target is to use human cells for making human iPSCs. Should I use human derived OSKM (hOSKM)? If yes then will these hOSKM factors also work for mouse cells to make mouse derived iPSCs and vice versa?
I will be highly thankful for valuable suggestions!