How to do Matrix inversion using FPGA ?

I need to implement matrix inversion in hardware. The size of the matrix can be anywhere from 50 *50 to 8*8. Are ready-made standard codes available or inbuilt modules available with FPGA...

15 February 2021 4,006 3 View

How to get the natural frequencies and mode shapes using several acceleration data?

I am using FDD (code I used - https://uk.mathworks.com/matlabcentral/fileexchange/50988-frequency-domain-decomposition-fdd) to extract the natural frequencies and mode shapes using the...

03 January 2021 4,038 2 View

Molecular Dynamics simulation using BIOVIA Discovery Studio ?

Dear All, I want to do the MD simulation studies of protein-ligand complex using BIOVIA Discovery Studio. Can anyone suggest me any tutorial (Video) for the same and also for the result analysis....

09 December 2020 7,132 2 View

What are the different units of determining the concentrations of gases in ambient air?

Gases in ambient air are measured in various units. Like ppm, ppb, percentages, microgtam per cubic meter etc. What are these exactly? I am new to the air field. earlier I worked with soil and...

27 November 2020 3,908 1 View

Are oil glands present in sandalwood? Or it is a byproduct of sapwood to heartwood formation?

I came to know that there is no oilglands in sandalwood and it is a byproduct during transformation of sapwood to heartwood. Is it true?

04 October 2020 8,216 2 View

Simulation time and Ensemble class for MD Simulation in Desmond ?

Hello All, I am working on MD simulation study using DESMOND for a protein-ligand complex (size of my protein is around 500 a.a). Can anyone please tell me on what basis I need to set the...

08 September 2020 8,529 2 View

How to get consensus of results produced by four miRNA target prediction algorithms (RNA22, miRanda, TargetFinder and psRNATarget)?

Different miRNA target prediction algorithms use different scores which is not comparable directly. So what is the most reliable way to get the consensus of results produced by different miRNA...

24 August 2020 9,659 4 View

Is it useful to have consensus of results produced by four miRNA target prediction algorithms (RNA22, miRanda, TargetFinder and psRNATarget)?

RNA22, miRanda, TargetFinder, and psRNATarget are four different algorithms aiming at finding miRNA targets. Many research-work claims at using a consensus of the result produced by these...

23 August 2020 5,058 5 View

Scholarly Recommender System?

Hi, Can anyone tell me any tool or suggestions as i want to seperate conference name from the title of paper? I AM LOOKING FOR CONFERENCE NAME NOT JOURNAL NAME.

10 August 2020 7,934 4 View

How to show PBC BOX/Unit Cell around protein-ligand complex in CHIMERA?

Hi All Can anyone tell me how to show PBC box/Unit cell around the protein-ligand sysytem in Chimera? I want to record the movie after their MD Simulation in Chimera. I know it can be done in...

16 April 2020 7,910 4 View

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02 March 2021 3,060 3 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Do you need the CMV enhancer before the CMV promotor for a proper function of CMV on the gene that follows?

I'm a student and I have to produce a cell line with a knockin for the NRF2 gene with GFP. I have to put a promotor in front of the GFP because the gene will be too far away from the promotor of...

28 February 2021 7,127 2 View

What could be some reasons why unstimulated monocytes are getting activated?

Im doing PBMC isolation -> CD14+ enrichment using magnetic beads -> stimulation setup. My negative control is just cells in cRPMI but they seem to get activated over and over again.

28 February 2021 7,883 3 View

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28 February 2021 9,936 2 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View