For those (still) interested in this question I will try to answer this question.

There are a number of tools available:

Heliquest: One of its features is the so-called lipid discrimination factor. It tells you whether a sequence (typically 18 AA long) is a potential lipid binding region or not.

https://www.researchgate.net/publication/23133533_HELIQUEST_A_web_server_to_screen_sequences_with_specific_a-helical_properties

See following reference for example:

https://www.researchgate.net/publication/47460373_The_prediction_of_novel_multiple_lipid-binding_regions_in_protein_translocation_motor_proteins_A_possible_general_feature

Eisenberg plot approach: Allows you to dissect on whether a sequence is a transmembrane or amphiphilic helix or presumably part of a soluble/globular protein.

https://www.researchgate.net/publication/16693014_Analysis_of_Membrane_and_Surface_Protein_Sequences_with_the_Hydrophobic_Moment_Plot

Or its related Heliquest based Eisenberg plot approach: Similar features as the original hydrophobic moment plot approach by Eisenberg but easy to use (and reproducible).

https://www.researchgate.net/publication/51733310_New_User-Friendly_Approach_to_Obtain_an_Eisenberg_Plot_and_Its_Use_as_a_Practical_Tool_in_Protein_Sequence_Analysis

See following references for examples:

https://www.researchgate.net/publication/230825800_Prediction_of_Lipid-Binding_Regions_in_Cytoplasmic_and_Extracellular_Loops_of_Membrane_Proteins_as_Exemplified_by_Protein_Translocation_Membrane_Proteins

https://www.sciencedirect.com/science/article/pii/S0005273614004507

MCPep: A Monte-Carlo approach (with a user-friendly webserver facility) that allows you to see whether a peptide has an affinity for lipid membranes and whether the peptide is bound in a surface or transmembrane kind of fashion.

https://www.researchgate.net/publication/225307205_Monte_Carlo_simulations_of_peptide-membrane_interactions_with_the_MCPep_web_server

See following reference for example:

https://www.researchgate.net/publication/268881276_Identification_and_in_silico_analysis_of_helical_lipid_binding_regions_in_proteins_belonging_to_the_amphitropic_protein_family