Can PGE1 have any effect on activated platelets?

25 June 2021 1 8K Report

Hello. I am testing PGE1 on my washed platelets, which is suppose to inhibit platelet activation. If the platelets have been left at room temperature for a while, and possibly activated, in this case will PGE1 not do anything? I am trying to understand why my platelets are not behaving as expected to PGE1.

Steingrimur Stefansson

Hi Rh Rj

. Have you tried treating PRP with PGE1 before washing? Also platelets need constant rocking motion.

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