Can Mycobacterium tuberculosis isolate be sensitive to first-line drug and resistant to second-line drugs in the same time??

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Samsher Singh

Yes, this happens.

Nakula et al., 2016 has studied this and published in J Microbiol Immunol Infect.recently.

Following is the link

http://www.ncbi.nlm.nih.gov/pubmed/26117528

Another one is by Jugheli etal 2008

http://www.ncbi.nlm.nih.gov/pubmed/18419893

Ahmed Elymani

Thank you Dr Samsher