Hi everyone,
I'm currently working on a project involving mitochondrial membrane potential, and I’ve come across the dye JC-1 (CBIC2) from Medchemexpress (HY-15534). I am wondering whether it could be used to stain tissue sections and how it can be done if possible.
Thank you in advance!
Hi, Fan Janice
This is not recommended.
JC-1 (CBIC2) is mainly used as a live cell dye and is usually more suitable for staining single cell suspensions or live cells. It is relatively less used for staining tissue sections, and the effect may not be as stable as dyes optimized for tissue sections.
If you need to stain tissue, it is recommended to digest the tissue sample into a single cell suspension before staining.
It should be noted that the state of cells in tissue sections and the density of tissue structure may affect dye penetration and staining effects.
The answer to this question comes from MedChemExpress (MCE) Technical Support.
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