I have searched actually. But, if its less than 10 then should I proceed with next experiment or not due to its less stability, for that thing i got confused.
Subhrajita Panda You are assuming that a zeta potential less than 10mV means less stability. Who taught you that?!! It simply isn't true. It may be true some of the time but it is a misleading rule. There's much more to stability than zeta potential.
In addition, -8mV is less than -10mV (in absolute terms) but what instrument did you use and how did you decide -10mV was some kind of threshold? How was that measured?
"should I proceed with next experiment or not due to its less stability" - what is the next experiment? Why not assess the stability? If you are measuring zeta potential, I assume you are using an instrument that can also measure particle size. Use that as an indicator of stability.
Yes, a zeta potential of -8 mV for exosomes is correct, but it indicates low stability. Typically, zeta potential values greater than ±30 mV suggest good stability in suspension.
Sabuj Kanti Nath "Typically, zeta potential values greater than ±30 mV suggest good stability in suspension." - this is a myth and is based on observations in the 1960s for red blood cells. There are other factors that influence stability. Certainly, in the absence of any other stabilizing mechanism, hydrophobic colloids possessing significant interfacial charge will experience a very large decrease in aggregation rate. But it is not a universal rule that zeta potential must be >30mV to achieve good stability.