The health promoting benefits and protective role of Indian spices has been reported in chronic disease with their role as a antimicrobial agent important to the prevention of NAFLD, heart disease, diabetes and Alzheimer’s disease. Consumption of spices is higher in various countries. Spice intake and its quantification (mg/day) in man has become important for risk assessment. The metabolism of various spices from the blood plasma is poorly understood and experimental research needs to be conducted to determine the amount of Indian spice (anti-bacterial activity) intake (mg/day) to avoid excessive release from bacteria of debris that involves the bacterial amyloid peptide and bacterial lipopolysaccharides (LPS) that are involved in the prevention of therapeutic antimicrobial drug (antibiotics) actions and endogenous antimicrobial inactivation in man and various species. The importance of caffeine (antimicrobial agent) in the developing world determines the intelligence quotient and thinking with Indian Spices intake over many years (brain contents) may interfere with cholesterol interacting proteins and caffeine’s effects as a cognitive enhancer and regulation of the circadian rhythm in the brain.
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INACTIVATION OF HEPATIC ANTIMICROBIAL METABOLISM
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INACTIVATION OF ENDOGENOUS ANTIMICROBIAL ACTIVITY
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BACTERIAL LIPOPOLYSACCHARIDES (LPS)
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SPICES AND ANTIMICROBIAL ACTIVITY AND FOOD PRESERVATION
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