If your DV is binomial, you can use GENLINMIXED command (https://www.ibm.com/docs/en/spss-statistics/24.0.0?topic=genlinmixed-examples-command)
If your IV is categorical and your DV is continuous, you can use MIXEED command. (https://www.ibm.com/docs/en/spss-statistics/24.0.0?topic=reference-mixed)
examples from UCLA (https://stats.oarc.ucla.edu/spss/seminars/spss-mixed-command/)
Note, once you enter these GENLINMIXED and MIXED function in SPSS, it is no longer a simple point-and-click, meaning you will have to write some codes. If that's the case, it might be beneficial if you learn R or Python.
Yes, Generalized Estimation Equation is available in SPSS, yet it doesn't discriminate in scale of measurement for independent and dependent variables.