Can blood serve as a surrogate for brain gene expression pattern?

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Craig Silver

No. There is a tissue specificity to many genes. For instance, genes that are well expressed in blood (hemoglobin?) would have a far reduced expression in brain tissue

Hassan Nima

this link is useful

Article Huntington’s disease blood and brain show a common gene expr...

regards

Beemnet Mengesha Kassahun

Interesting Question and Following for knowing more about the issue.