Hi,
I want to use potassium channel (BKca) opener as a standard for in vivo evaluation of my compound in rats for anti-hypertensive activity.
Dear Hina Iqbai:
Cilostazol, resveratrol, or chlorzoxazone is the opener of BK(Ca) channels.
You could try Hydrochlorothiazide, which is a thiazide diuretic which seems to activate BK channels. It may well require the beta1 subunit to do this.
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