We want to use a Zeiss Hyrax M40 microtome for plastic sectioning. It has never been used for plastic, and we have Leica Diamond blades that we were thinking of using. Any suggestions whether this combination can work?
I think even if it is possible after trial and error you will face difficulties. I suggest you use tungsten carbide blades which should be easily able to cut plastic and are much cheaper than diamond or sapphire blades.