I am studying the stability of nanoparticles at 37 degree for 3 days in different medium like water, PBS. Do they agglomerate to micrometer range?
Dear Sundara Raj,
The combination of Vander waals attraction forces and Brownian motion of nanoparticles would result in agglomeration.For colloidal dispersions the zeta potential value can be related to the stability. Colloids of high zeta potential (negative or positive) are electrically stabilized. Colloids with low zeta potentials tend to coagulate. So check for the zeta potential value of your nanoparticles, if its +/- 30mV to +/-40mV = moderately stable colloid +/-40 to =/-60mV= good stability and more than +/- 61 = excellent stability. If the value is lesser than 30 then there will be rapid coagulation and or incipient stability.
It depends on your materials. Can you please tell which kind of particle you are using?
I am using Zinc oxide nanoparticles and hollow silica nanoparticles
to my knowledge ZnO nanoparticles is not colloidal one. As a dispesion in water and PBS it might be remain stable for few days. Although I don not have any idea regarding sillica nanoparticles.
Thank you sudip, I find the particle size range in micrometer after 3 days storage at 37 degree. Its not in nano range, though the initial par.size were 215 and 430 nm
if your particles are charged ,then they won't agglomerate,,,,,otherwise they do
Dear Sundara Raj,
The combination of Vander waals attraction forces and Brownian motion of nanoparticles would result in agglomeration.For colloidal dispersions the zeta potential value can be related to the stability. Colloids of high zeta potential (negative or positive) are electrically stabilized. Colloids with low zeta potentials tend to coagulate. So check for the zeta potential value of your nanoparticles, if its +/- 30mV to +/-40mV = moderately stable colloid +/-40 to =/-60mV= good stability and more than +/- 61 = excellent stability. If the value is lesser than 30 then there will be rapid coagulation and or incipient stability.
yes it depend on zeta potential ..so measure that with tme interval (1, 2 ,3 day) and see how it is changing.
Dear Behin,
It really depends on the material of your nanoparticles. For example, titanium nanoparticles will re-agglomerate if left in the conditions you mention for 3 days. What is the material of your nanoparticles?
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