Can anyone please answer??How can we see the effect of beta blocker in isoprenaline induced heart failure in mice??

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Adejoke Yetunde Onaolapo

You would need to use echocardiography and/or electrocardiography machine to measure parameters of heart failure (wall thickness, ventricular pressure e.t.c . Biochemical markers of heart failure and histology of the cardiac muscle could also help.

Kenneth E. Robertson

Depends upon what "effect" you wish to measure. Agreed with Adejoke if you are looking at cardiac remodeling. If simple conduction effects, an ECG might be enough. The two added together, or a paced heart in solution, may be helpful also.