Specialization is imperative. It is, however, impossible for the specialist to understand the human being as a whole. Medicine has artificially separated the sick human being into small segments, and each fragment has its own specialist.When a specialist, from the beginning of her/his career, is confined to a minute part of the body, his knowledge of the rest is so rudimentary that she/he is incapable of thoroughly understanding even that part in which she/he specializes. The rest of the body also impacts the specialist's corner. The more eminent a specialist, the more dangerous he is.Although without specialists, science could not have progressed, before the result of the researches of the specialist is applied to humans, however, the scattered data of their analyses must be integrated in an intelligible synthesis. This is precisely where the specialist feels insecure and inadequate at the level of research.It is impossible to make use of the humongous mass of information -- facts -- accumulated by the specialists. For no one has undertaken to coordinate the data already obtained, and to consider the human being in her/his entirety. There might not be a better example than the entity known as migraine.Syntheses, as well as discoveries, demand exceptional mental power and physiological endurance, not merely the passing pf examinations or levels of formal education that stamp the label of specialist across the curriculum vitae.Breadth and depth of knowledge is rarely found in the same person. Such knowledge is systematically prised away from the specialist.As specialists corner the majority of tax-payers funds as research grants from Governments of advanced countries, it is no surprise that the bulk of research funding is wasted every year.The grants system is not without its own faults, as it involves peer review -- see attachments. Specialists lose common sense and the power of logic to make proper use of the data they collect with their researches, forget the meaning of the term biological, and place over-riding emphasis on the laboratory.Specialists lose the ability to manage the atypical patient, as they begin to believe that they know everything (even about nothing) in their own field.Much in Medicine is idiopathic, giving no chance for the specialist to maintain the illusion of being all knowledgeable.