Hydroxychloroquine Protonation in Blood and Cells - inconsistent information on claimed alkalinization inside targets, emphasis on Coronavirus?

Some researchers have claimed that Hydroxychloroquine (HCQ) can enter cells and make the environment more "alkaline" by soaking up protons. Many publications discuss only 2 nitrogen atoms that can...

08 August 2020 6,262 3 View

Do rats play a part in Covid-19?

The VIZIONS project in Vietnam in 2018 examined bat and rat urine and faeces. Alpha coronavirus was found in bats, beta in rats, with a comment that rats in China also carry coronavirus. So,...

10 May 2020 7,974 5 View

Organofluorine compounds in Kombucha?

Kombucha, a fermented Tea with low pH, contains substantial Fluoride in the form of Hydrogen Fluoride as well as the ion. Kombucha has been associated with many adverse effects, including acute...

12 February 2020 408 1 View

Could areas of high Fluoride ingestion be more susceptible to Coronavirus outbreaks?

The US Government Comparative Toxicogenomics database shows that Fluoride can inhibit Human immunity to viruses and pneumonia. Angiotensin I-Converting Enzyme (ACE), 2'-5'-Oligoadenylate...

03 February 2020 6,459 4 View

Do you have Fluoride analysis of Psammoma bodies isolated from Cancers or could you have them analyzed now from stored specimens?

I am updating my earlier review on the role of Fluoride doped Hydroxyapatite in Cancer and my current focus is on Psammoma Bodies which have been found, and identifed as high risk, in a very wide...

31 January 2019 3,477 1 View

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01 March 2018 8,712 2 View

Does anyone know of a means for testing worldview assumptions (apart from the IAT) and also assessing worldview (pre-theoretical) transformation?

I am interested in testing worldviews - at the assumption/presupposition/pre-theoretical (Weltanschauung) level. (This is not a test of espoused beliefs.) Harvard's IAT seems to do this in a very...

12 February 2017 8,608 3 View

Has anyone come across a study comparing the genetic profiles of C57BL/6J mice to outbred CD-1's?

Specifically in regards to inflammation and cartilage specific genes

03 February 2016 5,689 2 View

COVID-19: Are there any promising suggestions for interim medications while a vaccine is being developed?

See...

01 January 1970 2,745 100 View

HIV segments identified with India, Thailand and Kenya in Covid-19 receptor

01 January 1970 7,209 4 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

What is the production process of CaFe ferroalloys?

I looking for ferro calcium production process

03 March 2021 1,755 4 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

What does Servant Leadership mean today and in the future? What are the advantages and disadvantages?

In current time of many changes in business and world of work, a lot is said and reported about the importance, skills and benefits of leadership. Are soft skills becoming more and more important?...

02 March 2021 8,149 3 View

How optimize the Size Exclusion Chromatography?

Hello! I'll do a size exclusion chromatography, but I only have an open column, and I'll perform the peptide extraction from yeast, using buffer lysis (sodium phosphate 50 mM/NaCl 30 mM/DNAse and...

01 March 2021 2,215 2 View

Does anyone know an alternative product for cardiac Troponin T antibody for Immunofluorescence (Thermo # MA512960)?

We have been using Thermo Fisher anti-cardiac Troponin T antibody for immunofluorescence staining in FFPE mouse heart sections but it was recently discontinued. The literature shows it to be the...

01 March 2021 4,937 1 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Is there any one who can provide a donation of HPV detection and genotyping kits in exchange collaboration fors?

Warm greetings My name is Ayichew S. and I am doing my Ph.D. in Medical Microbiology (on Human papillomavirus). At this stage, I have almost completed a clinical sample Cervical swabs)...

25 February 2021 1,660 3 View