Science is fundamentally optimistic; per se, a science minded (not only designated Researchers) ought to have confidence in optimism. While conventional perception tells us that things are bad and getting worse, the science-minded perceive a good and promising future. Science is a system for exploration and innovation and is the engine of progress and prosperity. It can fire our imagination, can fuel economic growth and can form a path for youths in a competitive global marketplace. Our capability to handle today’s pressing issues; from providing energy security to curing illnesses to living sustainably requires the innovations from research. But, Research takes time and deserves firm commitment and investment. Looking to the present accomplishments and prospective picture of world's science and their impact on society at large, what makes you smile and what makes you worry?