In South Africa we are seeing unusual trends in cancers in an indigent population whose diet consists of mainly carbohydrates and cheap margarines. We are brainstorming a research project in this area and would like to share thoughts with others.
The European Prospective Investigation into Cancer and Nutrition (EPIC) conducted in 23 centres in 10 European countries is running since the early nineties of last century and still publishing findings regularly. For questions you may mail to [email protected] or [email protected]
Article European Prospective Investigation into Cancer and Nutrition...
Yes Colleen, other than EPIC , an ongoing multi-centre prospective cohort study designed to investigate the relationship between nutrition and cancer,, you can find a free available book about the world concensus in nutrition physical activity and cance, available at:.http://www.dietandcancerreport.org/expert_report/report_contents/index.php
2014 AICR Research Conference is going to take place at Washington in Oct 29-31
We at Integrated Cancer Treatment and Research Center, Pune, India are working in this field since years. we are now under scrutiny of our old data and found out some interesting links. currently study is going on and will reach you soon with some findings.
In northern Argentina there is a large group of natives , who have, an extremely low protein and a high starch and saturated fat, The main problema is that we do noave reliable disease stats.
Thank you all for the responses. We will be having a preliminary planning meeting of a research group on 20 September. I would most certainly like to draw on your expertise as we progress. Guillermo, we may be able to work in parallel. I think a study in your native population wont be all that different to ours. There is a lot to think about when setting up such a study. I will also most certainly look at the EPIC study and the others that have been mentioned above and use what we can from them.
Unfortunately you will probably find that all are studies made with european and caucasic. It would be interesting to find out if data can be extrapolated to black or oriental people.
IARC (International Agency for Research on Cancer), based in Lyon (France) is carrying a study at large scale to look for a link between diet and cancer prevalence, particularly in Africa.
See the abstract of their project on the link below
Here is a summary of one specific study as reported in the last few days.
Researchers from UK universities examined the diets and lifestyles of 20,000 men aged 50 to 69. They found that 10 helpings of tomatoes a week reduced the risk of prostate cancer by 18%. Pasta sauce, tomato juice, baked beans and the tomato puree topping on pizza all had a beneficial effect. The researchers think protection comes from a key chemical in the fruit, lycopene.
Men who consumed five portions a day of fruit and vegetables reduced their risk by 24% according to the research team. (Published in the journal Cancer Epidemiology, Biomarkers & Prevention,)
In the US the CDC has the Cancer Prevention Study which assesses diet and cancer risk. I believe the results of Cancer Prevention Study II have been reported.
I suppose there are numerous studies looking at the diet-cancer link -- but those have generally suffered from over-simplification. Better perhaps to look at links between biological mechanisms or processes that promote "cancer-causing" effects in the body and diet. Here at IHPR/UTHSCSA we are currently conducting a study called "Rx for Better Breast Health", which attempts to interrupt the process of inflammation by promoting an "Anti-inflammatory" (AI) diet. It targets TNF-alpha, CRP and various interleukins produced by adipose stromal cells. (This goes all the way back to Ian Clark's work at ANU regarding TNF levels and malaria). Basically we hope to reduce levels of TNFa, CRP and other "bad guys" through consumption of an anti-inflammatory diet and thereby reduce the likelihood of inflammatory-mediated cancer recurrence/spread/new incidence among breast cancer survivors. With respect to this question specifically, the literature is quite large. A search via Google or some other engine on keywords "Isothiocyanates" and "cancer" might be a good place to start. I'll look for some kind of recent overview of the evidence and post it here if I can.
Hello All, this is a link to an article which, while focusing on the specific beneficial effects of walnuts, provides an excellent and recent review of the diet-inflammation-cancer literature: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058555/ . It is a very nice article titled "Diet components can suppress inflammation and reduce cancer risk" by Elaine Hardman. Thanks to all for your excellent comments here... !
(2002) The American Cancer Society Cancer Prevention Study II Nutrition Cohort: Rationale, study design, and baseline characteristics. Cancer 94:2490–2501.
... and here is a link to our current work on the relationship between diet and cancer targeting the inflammation link: https://www.youtube.com/watch?v=a5h1sM8hm1k