Such transversions in a particular gene can alter the susceptibility to cancer.
Ola El-Habit
A list of chemicals can cause mutation and also, as a result can lead to cancer.
one of the T to G transversion in a report case from rare genetic mutations disease.
a novel T-to-G SNP transversion at nucleotide (nt) −567 of the HBG2 promoter. This mutation alters a GATA-1 binding motif to a GAGA sequence located within a previously identified silencing element. DNA-protein binding assays showed that the GATA motif of interest is capable of binding GATA-1 transcription factor in vitro and in vivo.
you can see Zhiyi Chen et al.,2008. in Molecular and cell biology reporting this case.
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