This is a question that will be raised by most oncologists. The corollary of this question is: Will this method raise glutathione in cancer cells as well, leading to their chemoresistance to chemotherapy? The literature suggests that when using actual glutathione precursors (like  available cysteine/cystine) will lead to what has been termed "selective modulation" of glutathione. This is a situation where cancer cells down-regulate GSH (negative feedback inhibition) but healthy cells increase their GSH levels. This has the potential of potentiating the effect of the chemo on tumor calls while decreasing chemotherapy side-effects. See http://www.ncbi.nlm.nih.gov/pubmed/18158761

Article Preclinical Pharmacokinetic Analysis of NOV-002, a Glutathio...

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