Hi, I want to esterify triglycine, the methodology I'm trying to follow indicates the use of thionyl chloride reagent. The thing is this is not sold in my country so I'm looking for a substitute. I would appreciate your recommendations
Hi Marcela
You can try to use the acetylchloride-Methanol system for the esterification of triglycerine. see the attached paper.
USE METHYL ACETATE
عيني تتم الاسترة عن طريق تفاعل الحامض الكاربوكسيلي والكحول وباستخدام بعض القطراة من حامض الكبريتيك
You can try to use the H2SO4-Methanol system for the esterification of triglycine hopefully it works.
Would you be able to get hold of TMS chloride and use this as an anhydrous source of HCL for the esterification.
Article A Convenient Synthesis of Amino Acid Methyl Esters
Oxalyl chloride, as suggested by Carlos, with a catalytic amount of DMF.
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