I am interested in studying the effect of my protein loss or overexpression on the Lamellipodium formation and dynamics. Can any one suggest a good human cell line (or even a mouse cell line) ?
All the fibroblast cell lines. 3T3 or C2C12, or others! Fibroblast plated on ECM give some nice adhesions, transfect well and you can follow migration for you functional analysis!