Any recommendations on ordering synthetic mature double-stranded (ds) microRNAs?

04 April 2014 1 7K Report

I am going to order chemically synthesized ds-microRNAs. Which do you recommend?

Should I order a perfectly matched ds RNA sequence, or a partially matched dsRNA identical to the mature microRNA itself?

Do the companies synthesize imperfectly matched RNA sequences?

Junaith Mohamed

Order miRNA mimics, which are small, chemically modified double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

http://www.lifetechnologies.com/us/en/home/life-science/epigenetics-noncoding-rna-research/mirna-profiling-/mirvana-mimics-inhibitors.html

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